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Longer HRT Use May Raise Breast Cancer Risk Wed Aug 11, 2010 6:07 am
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Longer HRT Use May Raise Breast Cancer Risk


Aug. 10, 2010 -- Hormone replacement therapy (HRT) and breast cancer risk have been long studied, and now a new analysis finds higher risks for normal-weight women and those on combination estrogen/progestin therapy.

While many studies have looked at the link, the new research sheds some new light on the topic, says researcher Tanmai Saxena, an MD/PHD student at the University of Southern California Keck School of Medicine in Los Angeles.

"The study further develops which women are at particular risk with HRT," he tells WebMD. Among his findings: "There is a risk associated with long-term HRT, both estrogen and combination [therapy]. As it turns out, the women who are thinner at menopause when they go on HRT have a higher risk of breast cancer."

The new analysis included 2,857 women participants in the California Teachers Study, all diagnosed with invasive breast cancer and followed on average for about 10 years.

The study is published in Cancer Epidemiology, Biomarkers & Prevention.

http://www.webmd.com/breast-cancer/news/20100810/longer-hrt-use-may-raise-breast-cancer-risk?src=RSS_PUBLIC
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Longer HRT Use May Raise Breast Cancer Risk Wed Aug 11, 2010 6:07 am
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