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How Much Does Lifestyle Affect Breast Cancer Risk? Sat Jun 25, 2011 7:25 am
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How Much Does Lifestyle Affect Breast Cancer Risk?


June 24, 2011 -- Women who are struggling to exercise regularly, maintain a healthy weight, or turn down a nightly glass of wine just got a bit of breathing room, at least as far as breast cancer is concerned.

A new study shows that these modifiable risk factors, even when taken together, account for a relatively small portion of a woman's overall breast cancer risk.

"I was surprised, a little bit, that you really do get a really different view of what is achievable by looking at absolute risks as opposed to relative risks, or attributable risks. The absolute risk reductions are kind of small it seems to me," says study researcher Mitchell H. Gail, MD, PhD, a senior investigator in the division of cancer epidemiology and genetics at the National Cancer Institute in Bethesda, Md.

Gail is no lightweight in the field of risk prediction. His research led to the development of a widely used tool that calculates a woman's five-year risk of breast cancer based on things that can't be controlled, like age, family history, ethnicity, how old she was when she had her first child, and her age at her first period. The tool calculates a number that's known as the "Gail score."

His new study, which is published in the Journal of the National Cancer Institute, shows that non-modifiable risk factors may be more important to determining overall breast cancer risk than things that are controllable, like body mass index (BMI), leisure time physical activity, or alcohol consumption.

http://www.webmd.com/breast-cancer/news/20110624/how-much-does-lifestyle-affect-breast-cancer-risk?src=RSS_PUBLIC
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How Much Does Lifestyle Affect Breast Cancer Risk? Sat Jun 25, 2011 7:25 am
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