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Combination Therapy May Treat Prostate Cancer Thu Jul 14, 2011 7:36 am
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Combination Therapy May Treat Prostate Cancer


July 13, 2011 -- For some men with early-stage prostate cancer, adding short-term hormone treatment to radiation therapy improves their chances of survival, according to a new study.

At the 10-year follow-up mark, 57% of those who got radiation alone survived, while 62% of those in the combination group were still alive, says William Shipley, MD, the Andres Soriano Professor of Radiation Oncology at Harvard Medical School.

The combination treatment made a difference not only in overall survival, but also in reducing deaths specifically from prostate cancer at the 10-year mark, he says. "In the ones with androgen deprivation therapy [hormone treatment], 4% died of prostate cancer," he tells WebMD. "With radiation alone, 8% did."

Men with intermediate risk of disease progression, as defined by several measures, benefited most from the combination treatment.

"If you have intermediate-risk prostate cancer and you are being treated with radiation, it will probably become standard treatment to have a short course of hormone treatment with that," Shipley says.

More than 240,000 U.S. men will be diagnosed with prostate cancer in 2011. Nine out of 10 will be diagnosed when the disease is in early stages, the researchers say.

The study is published in The New England Journal of Medicine.

http://www.webmd.com/prostate-cancer/news/20110713/combination-therapy-may-treat-prostate-cancer?src=RSS_PUBLIC
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Combination Therapy May Treat Prostate Cancer Thu Jul 14, 2011 7:36 am
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