Bay Area Forum for Asians

	Nutopia Forum Index

Nutopia Forum Index

Free Medical Info

Anti-Reflux Drugs, Antibiotics May Raise C. diff Risk

View previous topic :: View next topic

Page 1 of 1

	Anti-Reflux Drugs, Antibiotics May Raise C. diff Risk Thu Nov 03, 2011 5:28 am

Author

Message

DoctorNutopia

萬人迷

Joined: 06 Nov 2009

Posts: 2981

Post subject: Anti-Reflux Drugs, Antibiotics May Raise C. diff Risk

Anti-Reflux Drugs, Antibiotics May Raise C. diff Risk

Nov. 2, 2011 -- About 500,000 people in the U.S. become infected with the potentially fatal diarrhea bug Clostridium difficile(C. diff.) each year. Now a new study sheds light on who is most at risk -- and why.

Some people show evidence of C. diff in their gut but never have any symptoms. Others develop a range of symptoms from mild diarrhea to severe diarrhea, abdominal pain, bleeding, and fever. C. diff is typically seen in the health care setting, such as hospitals.

In the study of 4,143 people who were hospitalized, 2.8% were infected with C. diff and 3% had evidence of the bacteria, but no symptoms (colonization).

The study shows that people who test positive for the NAP1 strain of C. diff are most likely to suffer the symptoms. People who don't develop symptoms likely have evidence of other strains of this bug. What's more, the use of antibiotics, acid-suppressing proton pump inhibitors (PPIs), and older age all increase the risk of C. diff infection.

"The findings add to the understanding of Clostridium difficile infection and colonization and have implications for prevention and therapy," conclude researchers who were led by Vivian G. Loo, MD, of McGill University Health Center in Montreal.

Antibiotics and Anti-Reflux Drugs Antibiotics can wipe out bacteria, which can offset the balance between good and bad bacteria in the gut, setting the stage for C. diff infection.

PPIs such as Nexium, Prevacid, Prilosec, and Protonix may increase this risk in a different way. Stomach acid is one of the main defenses against bacteria. These drugs suppress acid, which may give bacteria the freedom to run rampant in your gut.

"We know the micro-organisms in the gut is a delicate balance of good and bad bacteria, which can be disrupted by many things," Robynne Chutkan, MD, says in an email. She is an assistant professor of medicine at Georgetown University Hospital in Washington, D.C. and founder and medical director at Digestive Center for Women in Chevy Chase, Md.

This includes the inappropriate or overuse of antibiotics, as well as changing the acidity level of the gastrointestinal tract with acid suppression. "We need to be more judicious with our prescribing patterns of these drugs," she says.

Anthony A. Starpoli, MD, agrees. He is the associate director of advanced esophageal endotherapy at Lenox Hill Hospital in New York City.

"A single dose of antibiotics increases your risk of C. diff by upsetting the flora," he says. "We have people calling their doctor and saying, 'I have a cold and a runny nose and need an antibiotic.' This is a big problem."

Antibiotics are not effective in treating a common cold caused by a virus. They are effective against bacterial infections.

http://www.webmd.com/digestive-disorders/news/20111102/anti-reflux-drugs-antibiotics-may-raise-c-diff-risk?src=RSS_PUBLIC

	Anti-Reflux Drugs, Antibiotics May Raise C. diff Risk Thu Nov 03, 2011 5:28 am

Author

Message

Special Offers!

萬人迷

Joined: 06 Nov 2009

Posts: 2981

Post subject:

Medical Info Blog

巨尻巨女 2007真情寫真 ??浜?绌?orrnet guochan.c.la，寮?涓芥兜涓???瀛?p?剧??
de2k松岛枫 http://www.sex8.cc@gmail.com/ Haruna Yabuki 日本女春暖花开性吧苍井空
rtys8cc qvod 小泽玛利亚电影 rouroufa ?╁??变汉浣???褰受乳
Janina Uhse hot 寮??靛?涓?绾х?? 春暖花开性吧有你。亚洲有码区 cqwww.net sex-56alav
涓??虫???辨?????????? 林私锺性感尤物小妹妹人体宋金咏及川奈央
陈艺真水岛津实快播比思特叶珏婕 tokyo hot ed2k 超光辉士 QVOD
筱崎雪枝 qvod 黑色丝袜美祢藤コウ ed2k 北原多香子迅雷亚洲转帖无码
崎吉直绪我的妈妈杨洁敏清雯藤蒲惠快播 meinv zouguangtu
info@caribbeancom.com jancy wong あいだゆあ楊怡人妻露穴
美女撕衣服 IWGB-006 苍井空339.YMVB 女孩奶女

Page 1 of 1

Theme designed by What Is Real!? 2005

All times are GMT + 8 Hours